Overview

Research Associate, Pilot Plant
Woburn, MA

Position Summary
Contribute to operations at the pilot plant conducting large-scale research and process development to support our gene therapy programs. Support upstream and downstream pilot-scale material supply operations and process evaluations to ensure timely product delivery and process transfer.

Responsibilities
• Apply scientific concepts to the scale-up and scale-down of mammalian cell culture and purification processes
• Perform maintenance and expansion of pilot cell cultures to support pilot production schedule
• Perform initial recovery & purification of harvest material, including filtration, chromatography and TFF
• Contribute to pilot support activities including solution preparation, raw materials procurement, data management, and routine lab maintenance
• Partner with Process Development scientists to ensure continuity of upstream and downstream process development
• Perform analytical testing, analyze data, interpret and present results
• Set up and maintain pilot equipment and analytical instrumentation

Qualifications:
• Bachelor’s or Master’s Degree in Biochemistry, Biology, Chemical/Bioengineering or other related scientific discipline with 0-5 years of biopharmaceutical experience
• Experience with cell culture process platforms and equipment, preferably single-use bioreactor (SUB) processes a plus
• Downstream processing experience (harvest, chromatography, TFF)
• Ability and desire to work in a fast-paced, start-up environment
• Strong collaboration and team-working skills
• Detail oriented; solid communication, interpersonal and organizational skills

Tracking

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